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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT3 All Species: 23.33
Human Site: T55 Identified Species: 42.78
UniProt: Q9UH03 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UH03 NP_061979.3 358 40704 T55 I E Q M R K K T M K T G F D F
Chimpanzee Pan troglodytes Q5R1W1 434 50272 V52 G F E F T L M V V G E S G L G
Rhesus Macaque Macaca mulatta XP_001102088 360 40906 T57 I E Q M R K K T M K T G F D F
Dog Lupus familis XP_857693 357 40495 T55 I E Q M R K K T M K T G F D F
Cat Felis silvestris
Mouse Mus musculus Q9Z1S5 350 40019 T55 I E Q M R K K T M K T G F D F
Rat Rattus norvegicus Q9WU34 358 40579 T55 I E Q M R K K T M K T G F D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505764 436 49083 A139 L E Q M R R K A M K Q G F E F
Chicken Gallus gallus Q5ZMH1 349 40206 L52 S G L G K S T L I N S L F L T
Frog Xenopus laevis Q63ZQ1 352 40432 L52 S G L G K S T L I N S L F L T
Zebra Danio Brachydanio rerio A2BGU8 361 40623 T67 I E Q M R K K T M K A G F D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40797 539 60125 A136 P N Q V Y R K A V K R G F E F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795119 662 73144 A314 Q E Q I R K K A L K R G F D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25342 322 37006 T51 G K S T L I N T L F A S H L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 98.8 99.1 N.A. 94.1 98.5 N.A. 54.8 43.2 43.8 77 N.A. 31.1 N.A. N.A. 34.1
Protein Similarity: 100 56.2 99.1 99.4 N.A. 94.9 99.1 N.A. 65.8 64.5 63.1 85.8 N.A. 45.2 N.A. N.A. 42.6
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 66.6 6.6 6.6 93.3 N.A. 40 N.A. N.A. 60
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 86.6 26.6 26.6 93.3 N.A. 66.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 58.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 24 0 0 16 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 54 0 % D
% Glu: 0 62 8 0 0 0 0 0 0 0 8 0 0 16 0 % E
% Phe: 0 8 0 8 0 0 0 0 0 8 0 0 85 0 62 % F
% Gly: 16 16 0 16 0 0 0 0 0 8 0 70 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 47 0 0 8 0 8 0 0 16 0 0 0 0 0 8 % I
% Lys: 0 8 0 0 16 54 70 0 0 70 0 0 0 0 0 % K
% Leu: 8 0 16 0 8 8 0 16 16 0 0 16 0 31 0 % L
% Met: 0 0 0 54 0 0 8 0 54 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 16 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 70 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 62 16 0 0 0 0 16 0 0 0 0 % R
% Ser: 16 0 8 0 0 16 0 0 0 0 16 16 0 0 0 % S
% Thr: 0 0 0 8 8 0 16 54 0 0 39 0 0 0 16 % T
% Val: 0 0 0 8 0 0 0 8 16 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _